The Use of Edge-Betweenness Clustering to Investigate Biological Function in Protein Interaction Networks

Ruth Dunn,Frank Dudbridge,Christopher M. Sanderson

The Use of Edge-Betweenness Clustering to Investigate Biological Function in Protein Interaction Networks

2005

Ruth Dunn
Frank Dudbridge
Christopher M. Sanderson

Background This paper describes an automated method for finding clusters of interconnected proteins in protein interaction networks and retrieving protein annotations associated with these clusters.

Keywords:

Genetics
Protein Interaction Networks
Cluster analysis
Protein Annotation
Computational biology
Function (biology)
Bioinformatics
Betweenness centrality
Cluster (physics)
Biology
Proteomics
Genome human
automated method

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