Certain aspects of diagnostic of osteopenia syndrome in traumatology and orthopedics.

: The osteopenia syndrome characterizing by progressing decrease of bone tissue mass and lowering of its strength due to damage of its micro-architectonics counts in the most significant medical social diseases. The timely detection of disorders of bone tissue remodeling is a complicated diagnostic task as far as laboratory diagnostic of osteo-deficiency conditions is based on finding indirect indices of bone tissue metabolism. The instrumental methods of evaluation of condition of bone structures provide no possibility to detect their early damages and to manage dynamic observation of implemented anti-resorption therapy. The study was carried out to develop complex approaches to laboratory instrumental diagnostic of osteo-deficiency conditions. The comprehensive laboratory instrumental examination of patients with deforming osteoarthritis of hip joint including evaluation of bone tissue mineral density, indices of calcium phosphorus metabolism, markers of bone resorption and bone formation, activity of inflammation process. The study established activation of bone resorption and inhibition of bone formation in patients with high activity of inflation process.