Recent Advancements in lung cancer treatment using receptor targeting.

Background In the cancer related deaths all over the world, lung cancer is at the top. The conventional treatment option available lacks specificity, causing cell toxicity, rapid clearance from the body and poor cancer cell penetration. Conclusion The nano delivery has reformed the treatment of lung cancer as selective drug uptake to the cancerous cell has been achieved by ligand targeted therapy. The ligand targeted therapy has been used for diagnostic and therapeutic purposes. This approach is based on the concept that receptors are overexpressed in expression in cancerous state compared to normal cells. The nanomedicines can reach to the cancerous cells through leaky vasculature surrounding cell.