Association Analysis between Cerebral Infarction and Coronary Stenosis by Coronary Computed

Background: The prevalence and mortality of cardiovascular and cerebrovascular disease have increased in recent years. Because there is an overlap between stroke and coronary heart disease, this case-control study was undertaken to elucidate the relationship between cerebral infarction and significant ( ≥ 50%) coronary artery stenosis by using coronary computed tomography angiography (CTA). Methods: We enrolled patients with cerebral infarction documented with neuroimaging who underwent coronary CTA and normal controls who visited Hyosung Hospital for a general health examination and underwent coronary CTA from January 1, 2012 to December 31, 2013. Results: Multivariable logistic regression revealed critical and independent correlations between cerebral infarction and significant stenosis ( ≥ 50%) of coronary arteries (odds ratio, 5.54; 95% confidence interval, 2.45-12.06; P < 0.001) Conclusion: Coronary CTA may be useful in patients with cerebral infarction for detection of increased risk of cardiovascular disease.