Decreased survival in normal karyotype AML with single-nucleotide polymorphisms in genes encoding the AraC metabolizing enzymes cytidine deaminase and 5'-nucleotidase.

Ingrid Jakobsen-Falk,Anna Fyrberg,Esbjorn Paul,Hareth Nahi,Monica Hermanson,Richard Rosenquist,Martin Höglund,Lars Palmqvist,Dick Stockelberg,Yuan Wei,Henrik Gréen,Kourosh Lotfi

Decreased survival in normal karyotype AML with single-nucleotide polymorphisms in genes encoding the AraC metabolizing enzymes cytidine deaminase and 5'-nucleotidase.

2013

Ingrid Jakobsen-Falk
Anna Fyrberg
Esbjorn Paul
Hareth Nahi
Monica Hermanson
Richard Rosenquist
Martin Höglund
Lars Palmqvist
Dick Stockelberg
Yuan Wei
Henrik Gréen
Kourosh Lotfi

De novo acute myeloid leukemia with normal karyotype (NK-AML) comprises a large group of patients with no common cytogenetic alterations and with a large variation in treatment response. Single-nuc ...

Keywords:

5'-nucleotidase
Immunology
Myeloid leukemia
Karyotype
Single-nucleotide polymorphism
Cancer research
Cytidine deaminase
Gene
Cytarabine
Fms-Like Tyrosine Kinase 3
Biology

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