TEN-YEAR EXPERIENCE OF MODIFIED-FAT DIETS ON YOUNGER MEN WITH CORONARY HEART-DISEASE

Abstract One hundred men, 30-50 years old, with confirmed coronary-artery disease and past myocardial infarction, were placed on a 28% fat diet after weight reduction. This group was matched with a similar group not under dietary management. Over a period of 10 years there were significant reductions in serum-lipids in the diet-managed group compared with the control group. In this predominantly lipoprotein-phenotype-IV group, using a diet containing less than 9% of calories as saturated fat and less than 400 mg. exogenous cholesterol daily, the degree of unsaturation of the diet did not appear to influence either serum-lipid values or mortality-rates. After 10 years, the diet-managed group had a 17% greater survival-rate than the control group.