Macrophage colony-stimulating factor induces the proliferation and survival of macrophages via a pathway involving DAP12 and |[beta]|-catenin

Macrophage colony-stimulating factor (M-CSF) induces the proliferation of mononuclear phagocytes, and DAP12 is needed for their function. Colonna and colleagues show that DAP12 is also needed for M-CSF-induced stabilization of β-catenin.