Synthesis and evaluation of aminomethyl dihydrocinnamates as a new class of PPAR ligands.

2006 
PPAR ligands with varied subtype selectivity have been synthesized using an achiral aminomethyl dihydrocinnamate template. Several compounds in this series have demonstrated potent plasma glucose and triglyceride lowering capability in rodent models of type 2 diabetes.
    • Correction
    • Source
    • Cite
    • Save
    • Machine Reading By IdeaReader
    20
    References
    2
    Citations
    NaN
    KQI
    []