Progress in treatment of acute kidney injure with adipose-derived mesenchymal stem cells

Cell-based therapy and regenerative medicine offer a paradigm shift in regard to various diseases causing tissue or organ damage. Recently, many authors have focused their attention on adipose-derived mesenchymal stem cells (ADMSCs) for their capacity to differentiate into many cell lineages. Acute kidney injury (AKI), as a common emergency, has high morbidity rate and relatively limited treatment. This review will summarize the mechanism of ADMSCs in treatment of acute kidney injury, and hope to lay a foundation for future research. Key words: Mesenchymal stem cell transplantation; Adipocytes; Kidney/IN; Kidney diseases/SU; Review