The Influences of Electromagnetic Field Irradiated by High-Voltage Transmission Lines with 50Hz on Properties of Cells - TI Journals

Abstract: The influences of low-frequency electromagnetic field irradiating by high-voltage transmission lines on signal transduction of cell in spleen cells of the rates have been studied by molecular-biology techniques. The spleen cells are extracted from skilled rats, which are exposed in the electromagnetic field of high-voltage transmission lines with 4000V/m and 0.09-0.1G and 50Hz about 400days. The quantity or level of Phosphorylation of signal transducer and activator of transcription (STAT3) in JAK-STAT signal transduction pathway of spleen cells, which are stimulated and unstimulated by IL-2, respectively, are detected by the immunoblotting and immunobiochemistry. The results show that the expression of phospho- STAT3 in spleen cell stimulating by IL-2 differ from that in the unstimulated cell. The former is significantly large than the latter. This shows that signal transduction of cell is affected by this electromagnetic field.