IG20 (MADD splice variant-5), a proapoptotic protein, interacts with DR4/DR5 and enhances TRAIL-induced apoptosis by increasing recruitment of FADD and caspase-8 to the DISC.

Madhu Ramaswamy,Elena V. Efimova,Osvaldo Martinez,Nirupama Mulherkar,Surya P. Singh,Bellur S. Prabhakar

IG20 (MADD splice variant-5), a proapoptotic protein, interacts with DR4/DR5 and enhances TRAIL-induced apoptosis by increasing recruitment of FADD and caspase-8 to the DISC.

2004

Madhu Ramaswamy
Elena V. Efimova
Osvaldo Martinez
Nirupama Mulherkar
Surya P. Singh
Bellur S. Prabhakar

IG20 (MADD splice variant-5), a proapoptotic protein, interacts with DR4/DR5 and enhances TRAIL-induced apoptosis by increasing recruitment of FADD and caspase-8 to the DISC

Keywords:

Caspase 8
Cancer research
Caspase
splice
FADD
Alternative splicing
Apoptosis
Molecular biology
Carcinogenesis
Death-inducing signaling complex
Biology

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