Co-production of carbonic anhydrase and phycobiliproteins by Spirulina sp. and Synechococcus nidulans

Abstract The aim of this work was to study the co-production of the carbonic anhydrase, C-phycocyanin and allophycocyanin during cyanobacteria growth. Spirulina sp. LEB 18 demonstrated a high potential for simultaneously obtaining the three products, achieving a carbonic anhydrase (CA) productivity of 0.97 U/L/d and the highest C-phycocyanin (PC, 5.9 μg/mL/d) and allophycocyanin (APC, 4.3 μg/mL/d) productivities. In the extraction study, high extraction yields were obtained from Spirulina using an ultrasonic homogenizer (CA: 25.5 U/g; PC: 90 mg/g; APC: 70 mg/g). From the same biomass, it was possible to obtain three biomolecules that present high industrial value.