Prevalência das infecções pelos vírus das hepatites em localidade rural sob influência de um projeto de mineração

2010 
Definir a frequencia de marcadores das infeccoes pelos virus das hepatites A-D na Comunidade Cafe Torrado, Juruti, Oeste do estado do Para, Brasil, atualmente sob a influencia de um projeto de mineracao. Metodo: estudo de campo, transversal de prevalencia, onde amostras de soro coletadas em novembro de 2009, na Comunidade Cafe Torrado, foram examinadas por tecnica imunoenzimatica para as hepatites A, B e C. Resultados: incluidos no estudo 232 individuos, sendo 53% do sexo feminino. A analise mostrou prevalencia global de 78% para o anti-VHA total, com 75% de suscetiveis na faixa etaria de 1 a 4 anos. Com relacao a hepatite B, o estudo mostrou prevalencia total de 2,2% para algum marcador do VHB; nao foram detectados portadores do virus da hepatite B; 1,3% apresentaram indicadores de infeccao pregressa; 0,9% anti-HBc+ isolado; 37,1% com perfil compativel de protecao vacinal; 60,8% eram susceptiveis ao VHB e o perfil sorologico vacinal ate os 19 anos se mostrou em 44,4%. Nao foram detectadas pessoas infectadas pelo VHC. A ausencia de portadores do VHB tornou desnecessaria a realizacao dos testes HBeAg, anti-HBe e anti-HD total. Conclusoes: a comunidade Cafe Torrado apresentou alta endemicidade para o VHA; moderada endemicidade para o VHB, onde a deteccao de susceptiveis reitera a importância da vacinacao e a necessidade em amplia-la no municipio. Para o VHC e VHD foi demonstrada baixa endemicidade. To define the frequency of markers of infections by the Hepatitis A-D viruses in the Cafe Torrado Community, Juruti, West of Para, Brazil, currently under influence of a mining project. Methods: study, transversal; serum samples were collected in November 2009 in Cafe Torrado Community. These samples were analyzed by immunoenzymatic technique for Hepatitis A, B and C. Results: 232 individuals were included in this study; 53% were female. The analysis showed a global prevalence of 78% for anti- HAV, with 75% of susceptible in the age group of 1-4 years old. This study showed total prevalence of 2.2% for any marker of HBV; virus carriers were not detected; 1,3% had markers of previous infection; 0.9% had isolated anti-HBc+.37.1% had a compatible profile with vaccine protection; 60.8% were susceptible to HBV and the vaccine serum profile up to 19 years of age was 44.4%. HCV-infected people were not detected. The absence of HBV carriers made the HBeAg, anti-HBe and anti-HD tests unnecessary. Conclusions: the Cafe Torrado Community showed high endemicity for HAV; mild endemicity for HBV, but the detection of susceptible strengths the importance of the vaccine and the need of amplifying it in the city. HCV and HDV had low endemicity.
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