Analysis on mycoplasma infection and antimicrobial resistance among female patients.

Objective To analyze the infection and antimicrobial resistance of Ureaplasma urealyticum(Uu)and mycoplasma hominis(Mh)among female patients,and provide data of epidemiology and guidance for reasonable application of antibiotics.Method Cervical secretion was identified and the antibiotic susceptibility was detected with Mycoplasma IST 2 Reagent Box from France.Result Of the total 2 135 cases,1 166 were infected with Mycoplasma,the positive rate was 54.6%,among which 1 017 cases were Uu positive(47.6%),32 cases were Mh positive(1.5%),117 cases were both Uu and Mh positive(5.5%);The susceptibility of the pathogens to all the 9 antimicrobial agents from high to low were Pristinamycin(99.8%),Josamycin(99.6%),Doxycycline(96.3%),Tetracycline(94.4%),Clarithromycin(85.6%),Azithromycin(77.6%),Erythromycin(75.6%),Ofloxacin(28.4%)and Ciprofloxacin(22.8%),respectively.Conclusion Mycoplasma(especially Uu)is the main pathogen of urogenital tract infections among women,and their susceptibility to antibiotics varies greatly.Antibiotics such as Pristinamycin,Josamycin and Doxycycline to which the pathogens are sensitive should be used to deal with the infection of Uu and Mh.Mycoplasma shows a high resistance to Quinolones,which should be paid highly attention in clinical practice.