Constituents of Beauveria bassiana 101A having enhancement of the neurite outgrowth and pharmaceutical composition containing the same
2002
PURPOSE: Provided is a beauveria bassiana 101A extract containing an active compound which has excellent activity in nerve cell outgrowth without cytotoxicity. The extract and active compound separated therefrom can reduce atrophy and damages caused by degenerative cerebral diseases including Parkinson's disease and stroke. CONSTITUTION: The active compound from beauveria bassiana extract is represented by formula 1, wherein R is C17 or C19 of alkyl group. The pharmaceutical composition using the active compound from beauveria bassiana extract for treatment or prophylaxis of cerebral diseases comprises one or more selected from a group consisting of 1,7-dimethyl-xanthine, uracil, urea, betain, and tyrosine, as an active compound.
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