Abstract P341: Melanocortin Receptor 4 Activation Mediates Leptin-Induced Sensitization of the Angiotensin II-Elicited Hypertensive Response in Mice

Baojian Xue,Terry G. Beltz,Fang Guo,Alan Kim Johnson

Abstract P341: Melanocortin Receptor 4 Activation Mediates Leptin-Induced Sensitization of the Angiotensin II-Elicited Hypertensive Response in Mice

2018

Baojian Xue
Terry G. Beltz
Fang Guo
Alan Kim Johnson

Obesity has been shown to promote the renin-angiotensin system (RAS) activity and inflammation in the hypothalamus that increase BP and sympathetic activity. Our previous studies using an Induction...

Keywords:

Endocrinology
Diabetes mellitus
Melanocortin 4 receptor
Angiotensin II
Sensitization
Leptin
Medicine
Internal medicine

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