The status and prospects of niacin and its combination therapy with statins

Niacin,a broad-spectrum lipid-regulating agent,can significantly lower plasma triglyceride and raise the high density lipoprotein-cholesterol.Extended-release niacin added to statins monotherapy could further modify the lipid profile and reduce residual cardiovascular risk.This combination therapy provides a safe,effective and economical treatment for clinicians and may be superior to other drugs combined with statins.