Effect of design of standard metallic stents on neointimal hyperplasia and restenosis

: Coronary stents became an integral part of treatment of ischemic heart disease (IHD). Number of percutaneous coronary interventions (PCI) in patients with IHD in Russia constantly growing. At a certain stage of development of interventional cardiology drug eluting stents (DES) were created and became actively used. Compared with metallic stents (MS) drug eluting stents allow to substantially reduce risk of restenosis. However DES did not replace MS and the latter are still used in about 50% of PCI in Russia. Design of standard MS and thickness of struts might affect extent of neointimal proliferation which develops after stent implantation and eventually determines remote outcomes of IHD treatment. Thereby choice of optimal MS remains an actual problem. In this review we present results of clinical studies which compared MS with different design and thickness of struts.