Genetic association of zinc transporter 8 (ZnT8) autoantibodies in type 1 diabetes cases

Joanna M. M. Howson,Stephanie Krause,Helen Stevens,Deborah J. Smyth,Janet M. Wenzlau,Ezio Bonifacio,John C. Hutton,Anette-G. Ziegler,John A. Todd,Peter Achenbach

Genetic association of zinc transporter 8 (ZnT8) autoantibodies in type 1 diabetes cases

2012

Joanna M. M. Howson
Stephanie Krause
Helen Stevens
Deborah J. Smyth
Janet M. Wenzlau
Ezio Bonifacio
John C. Hutton
Anette-G. Ziegler
John A. Todd
Peter Achenbach

Aims/hypothesis Autoantibodies to zinc transporter 8 (ZnT8A) are associated with risk of type 1 diabetes. Apart from the SLC30A8 gene itself, little is known about the genetic basis of ZnT8A. We hypothesise that other loci in addition to SLC30A8 are associated with ZnT8A.

Keywords:

Autoantibody
Genetic association
Type 1 diabetes
Zinc Transporter 8
Diabetes mellitus
Genotype
Endocrinology
Genetics
SLC30A8
Human leukocyte antigen
Biology
Internal medicine

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