Synthesis of a 5-Azaindole Phosphonic Acid as a Computationally Designed Inhibitor of the Low Molecular Weight Phosphatase HCPTP
2006
A computationally designed inhibitor of human low molecular weight protein tyrosine phosphatase, HCPTP, was synthesized. The target compound is based on a 5-azaindole heterocyclic core bearing a phosphonic acid side chain. Its synthesis was accomplished in ten steps.
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