Double Axially Chiral Bisphosphorylimides Catalyzed Highly Enantioselective and Efficient Friedel–Crafts Reaction of Indoles with Imines

BINOL and VAPOL-derived double axially chiral bisphosphorylimide catalysts enable the atom-economical and highly enantioselective Friedel—Crafts reaction between indoles and N-tosylimines with a low catalyst loading.