ВОПРОСЫ ДЕСТРУКЦИИ И РЕГЕНЕРАЦИИ КОСТНОЙ ТКАНИ В АСПЕКТЕ СУДЕБНО-МЕДИЦИНСКИХ ОЦЕНОК

Bone regeneration of patients with osteoporosis takes significantly longer than the rehabilitation period of individuals without bone pathology. This is due to the predominance of destructive processes in the setting of osteoblastic reaction weakened by osteoporosis, persistent inflammatory reactions, as well as proliferating connective tissue. Aim . Тo study the nature and dynamics of processes involved in the destruction and regeneration of bone tissue under various conditions, taking forensic medical assessment into account. Material and methods . We studied the autopsy and biopsy material of bone tissue using clinical-instrumental and histological research methods. Results . Using atomic force microscopy, it was found that in individuals with osteoporosis the formation of endosteal callus exhibits features associated with the impaired interlacing of collagen fibres due to the expanded space between them, and, as a result, an impaired connection between osseous structures with a low level of mineralisation. Conclusion . In accordance with paragraph 24 of Order 194n On the Approval of Medical Criteria for Determining the Severity of Harm to Human Health verified systemic osteoporosis that was the setting for the fracture, which in fact is a pathological fracture, should not be considered as damage to health.