Biomolecular modeling thrives in the age of technology
2021
The biomolecular modeling field has flourished since its early days in the 1970s due to the rapid adaptation and tailoring of state-of-the-art technology. The resulting dramatic increase in size and timespan of biomolecular simulations has outpaced Moore’s law. Here, we discuss the role of knowledge-based versus physics-based methods and hardware versus software advances in propelling the field forward. This rapid adaptation and outreach suggests a bright future for modeling, where theory, experimentation and simulation define three pillars needed to address future scientific and biomedical challenges. The field of biomolecular modeling has thrived by exploiting state-of-the-art technological advances. In this Perspective, the role of software and hardware advances, and the disparity and synergy between knowledge-based and physics-based methods are discussed and explored.
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
161
References
7
Citations
NaN
KQI