Cu- and Pd-catalyzed asymmetric one-pot tandem addition-cyclization reaction of 2-(2 ‘,3 ‘-alkadienyl)-beta-keto esters, organic halides, and dibenzyl azodicarboxylate: An effective protocol for the enantioselective synthesis of pyrazolidine derivatives
2004
Optically active pyrazolidine derivatives have been constructed by the Cu- and Pd-catalyzed asymmetric one-pot tandem addition−cyclization reaction of 2-(2‘,3‘-dienyl)-β-ketoesters, organic halides, and dibenzyl azodicarboxylate. The absolute configurations of the final products depend on the structure of the ligand.
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