SAT0415 HIGH BODY FAT OF TRUNK IS POSITIVELY CORRELATED WITH SERUM URIC ACID IN MALE GOUT PATIENTS

Background: Obesity is an important risk factor of gout which is defined by body mass index (BMI). However, BMI has been challenged for the limitation of failure to differentiate comprising tissues of the body. More accurate body composition (BC) has been frequently recommended to assess metabolic status. Objectives: To investigate the characteristics of BC in gout patients and its clinical significance. Methods: Consecutive gout patients who fulfilled the 2016 ACR/EULAR classification criteria were recruited between June 2017 and December 2018. BC was assessed by bioelectric impedance analysis including body fat percentage (BF%), the mass and distribution of muscle and fat in trunk and appendicular extremities. Demographic information, clinical characteristics and comorbidities were collected. Overfat was defined by BF% ≥25% for male and ≥35% for female. Results: Among 362 recruited gout patients, 96.1% were male and the median age was 38 (30, 50) years, mean serum uric acid (sUA) was 9.2±2.2mg/dl, 18.0% presented tophi. The mean BF% was 25.8±6.4% with 53.6% overfat. Male gout patients with overfat (53.7%) showed more affecting joints, higher sUA and higher prevalence of comorbidities than those without overfat (P Conclusion: The characteristics of fat distribution in male gout patients is more in trunk and trunk BF% is positively correlated with sUA. Disclosure of Interests: None declared