Abstract 12399: Differences in Culprit Plaque Morphology in Patients with ST Elevation Myocardial Infarction versus Non ST Elevation Acute Coronary Syndrome: Optical Coherence Tomography Study

Objective: To compare the differences in the culprit plaque morphology between patients with ST elevation myocardial infarction (STEMI) and those with non ST elevation acute coronary syndrome (NSTE ACS). Methods: A total of 403 patients were enrolled in this study: 108 with STEMI and 295 with NSTE ACS. All patients underwent OCT during the acute phase. Results: Lipid plaques accounted for 92.6% and 86.1% of the culprit lesion in STEMI and NSTE ACS group, respectively. The STEMI patients had thinner fibrous cap (54.9±22.7 µm versus 75.4±38.7µm, P<0.001), greater lipid core arc (227.3±60.4°vs 213.6±55.6°,P<0.05) and longer lipid core length (15.6±6.8mm vs 13.3±7.4mm,P<0.01). The size of the ruptured cavity were greater in the STEMI than in the NSTE ACS group: depth (0.7±0.4.mm vs 0.6±0.5mm, P<0.05), the length (2.8±1.8mm vs 1.8±1.1mm, P<0.001) and average cross sectional area (0.9±0.7mm2 vs 0.6±0.6mm2,P<0.01). The rupture site was more frequently proximal to the minimal lumen in the STEMI group compared to ...