The Comparative Analysis of Preterm Premature Rupture of Membranes with or without Obviously Predisposing Factors

Objective:To investigate predisposing factors of preterm premature rupture of membranes(PPROM) and its effects on the maternal and perinatal outcomes.Methods:The clinical data of 494 cases of PPROM from November 2004 to January 2012 were retrospectively analyzed.494 cases were divided into two groups.287 patients with obviously predisposing factors were in the observation group[group PPROM(A)],while the others were as in control group [group PPROM(B)].General conditions,mode of delivery and pregnancy outcomes were compared between the two groups.Results:①In group PPROM(A),mean maternal age and mean undesirable previous obstetric history were higher than that of group PPROM(B) (29.72±4.81 vs 28.50±4.49,P0.05;4.9%vs 0,P0.05).While the mean gestational age at delivery was significant lower than that in group PPROM(B)(33.01±2.40 vs 34.01±2.29,P0.01).②Compared to group PPROM(B),the rate of vaginal deliveryof group PPROM(A) was significantly lower(33.1% vs 73.4%,P0.01) and cesarean section rate was significantly higher(63.8% vs 25.6%,P0.01).③The constituent ratio of maternal complications in group PPROM(A) was higher than that in group PPROM(B)(31.7% vs 21.3%,P0.01),the intraamniotic infection in group PPROM(A) was higher than that in group PPROM(B)(9.1% vs 0,P0.01).④Preterm infants in group PPROM(A) had a lower birth weight and lower 1 min Apgar scores than those in group PPROM(B) (P0.01).And neonatal morbidity in group PPROM(A) were higher than the group PPROM(B) (P0.05).There was no statistical difference in other aspects between these two groups(P0.05).Conclusions:PPROM with obviously predisposing factors has a higher perinatal morbidity.Maternal age,undesirable previous obstetric history and maternal health may have an effect on pregnancy outcomes.So actively find and deal with predisposing factors of PPROM,and strengthening the prenatal examination and perinatal care,are not only important to decrease the rate of cesarean section and perinatal morbidity,but also and to improve the pregnancy outcomes.