Noscapine derivative, and preparation method and application thereof

The invention relates to a noscapine derivative having the structural general formula represented by the formula I, and a preparation method and an application thereof, wherein an R substituent group in the derivative is aryl, a heterocyclic group, alkyl, alkyl carboxylic acid or alkyl amide. Through chemical modification and functional group introduction of a narcotine mother ring structure, the anticancer activity is enhanced, so as to obtain an anticancer drug having high activity and low side effects.