CORRELATION BETWEEN CHANGES IN BODY MASS INDEX AND BLOOD LIPIDS WITH PROGRESSION OF NON-TARGET CORONARY LESIONS IN PATIENTS AFTER CORONARY STENT IMPLANTATION

Aim: To examine the relationship of body mass index (BMI) and blood lipids with progression of non-target coronary lesions in patients after percutaneous coronary intervention (PCI). Materials and Methods: A total of 3071 patients undergoing PCI hospitalized from January 2013 to December 2016 at the Beijing Anzhen Hospital were enrolled. All patients were readmitted due to chest pain within 6–24 months, divided into two groups. Group A (n=1541) experienced progression in non-target lesions while Group B (n=1530) not. The distribution of BMI and blood lipid levels were evaluated. Results: At the first hospitalization, the BMI and LDL levels of patients in two Groups were similar. On the second hospitalization, the BMI of Group B was significantly lower than Group A (Group B: 25.49±2.94 kg/m 2 VS. Group A: 26.2±3.16 kg/m 2 , P<0.001). Furthermore, the proportion of patients in Group B with BMI within the normal range was significantly higher than Group A (Group B: 51.6% VS. Group A: 35.3%, P<0.001). Additionally, the LDL level in Group B was significantly lower than in Group A, while the LDL-C target-level achievement ratio for patients in Group B was higher than in Group A. Logistic regression showed LDL-C level, BMI and statin administration after PCI were correlated with progression of non-target lesions. Conclusion: Patients who did not experience progression of non-target lesions after PCI had significantly higher ratios of normal BMI on second hospitalization and LDL target-level achievement ratios than patients with progression of non-target lesions.