Biofilm: Clinical Experience

Bacteria in biofilms are very resistant on the treatment with dressings or antibiotics because of their extracellular polysaccharide matrix on a surface. We have indirect clinical indicator for biofilm and less possibilities for real identification. Surgical debridement is most successful for removing the biofilm, particularly in combination with antiseptics. Dressings with silver, polyheksanide, iodine, octenidine, and honey are sufficiently effective only as a part of multimodal therapy.