Analgesic Properties of Oral Sucrose During Routine Immunizations: In Reply

We appreciate the views expressed by Dr Dilli in response to our study1 and wish to clarify several points that were made. First, early investigators of sucrose analgesia considered proportion, percentage, or duration of cry to be valid indicators of pain in infants.2–4 Cry may give some indication of pain or distress5; however, cry alone does not confirm or deny infant pain. Allen et al4 reported that 12% sucrose (not the 24% used in our investigation) …