Variations of Urinary Sodium Concentration After Contrast Media with Different Osmolality

The consequences of water-soluble contrast media (CM) on different renal functions are not well known. Their effect on sodium and water elimination has been compared to that of osmotic diuretics. Gruskin et al. [2] have shown that three-iodinated CM induce increased sodium elimination as prolonged as CM elimination. The experiments carried out by Ziegler et al. [3, 4] show that ionic CM inhibit active sodium transport. We have studied the evolution of urinary sodium concentration [Na+] u in man after CM with different osmolality.