Resolution of 4-Hydroxy-2-cyclopentenone Derivatives by HPLC on Cellulose Triphenylcarbamate Derivatives

Yoshio Okamoto,Ryo Aburatani,Mitsunobu Kawashima,Koichi Hatada,Noriaki Okamura

Resolution of 4-Hydroxy-2-cyclopentenone Derivatives by HPLC on Cellulose Triphenylcarbamate Derivatives

1986

Yoshio Okamoto
Ryo Aburatani
Mitsunobu Kawashima
Koichi Hatada
Noriaki Okamura

Trialkylsilyl ethers of 4-hydroxy-2-cyclopentenone, which are the key compounds for the syntheses of prostaglandins, were completely resolved on chiral HPLC columns packed with cellulose triphenylcarbamate derivatives.

Keywords:

Cyclopentenone
Chiral column chromatography
Prostaglandin
High-performance liquid chromatography
Enone
Cellulose
Chromatography
Organic chemistry
Chemistry

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