The effect of cryopreservation and transplantation factors on the morphofunctional state of the thyroid in dogs

: Influence of transplantation of non-specific factors (denervation, delymphatization, surgical trauma, ischemia, changes in blood supply conditions) as well as the effect of cryopreservation (-196 degrees C) on morphological structure and ability for secretion of thyroid hormones and response to TS stimulation were studied using the model of extracorporal biological perfusion in isolated thyroid of dogs. The results of biochemical and morphological investigations of thyroid in different conditions of perfusion showed, that it had preserved its main functional and morphological characteristics under the action of transplantation of nonspecific factors and extremely low temperatures.