Analgesic and anti-inflammatory effect of Lidan Huayu tablet

[Objective] To observe the analgesic and anti-inflammatory effects of Lidan Huayu tablet(LHT).[Methods] Compared with aspirin,the analgesic effect of LHT on mice were investigated with hot plate method and aceticacid-induced body twist method;Anti-inflammatory actions of LHT and aspirin were observed on the models of xylene-induced auricular swelling,celiac capillary permeability of the blood vessl by acetic-acid in mice.[Results] LHT could increase the pain threshold obviously,and the effect maintained as long as 4 hours upwards,and reduce the frequency of body twist,and with the increase of dosage,the pain threshold was higher and higher;and the number of times of twisting body was lower and lower.LHT could inhibit xylene-induced auricular swelling and body twisting response reaction by acetic acid in mice.[Conclusion]Lidan Huayu tablet possesses strong analgesic and anti-inflammation effects.