Simvastatin inhibits cytokines in a dose response in patients with rheumatoid arthritis

Michelly Cristiny Pereira,Pablo Ramon Gualberto Cardoso,Laurindo Ferreira da Rocha,Moacyr Jesus Barreto de Melo Rêgo,Sayonara Maria Calado Gonçalves,Flaviana Alves dos Santos,Marina Rocha Galdino-Pitta,Andréa Tavares Dantas,Angela Luzia Branco Pinto Duarte,Maira Galdino da Rocha Pitta

Simvastatin inhibits cytokines in a dose response in patients with rheumatoid arthritis

2014

Michelly Cristiny Pereira
Pablo Ramon Gualberto Cardoso
Laurindo Ferreira da Rocha
Moacyr Jesus Barreto de Melo Rêgo
Sayonara Maria Calado Gonçalves
Flaviana Alves dos Santos
Marina Rocha Galdino-Pitta
Andréa Tavares Dantas
Angela Luzia Branco Pinto Duarte
Maira Galdino da Rocha Pitta

Objective and design To evaluate the effects of simvastatin in peripheral blood mononuclear cell (PBMC) cytokines profiles and correlate with the disease state of rheumatoid arthritis (RA) patients.

Keywords:

Diabetes mellitus
Biology
Rheumatoid arthritis
Simvastatin
Biochemistry
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Peripheral blood mononuclear cell
Disease
Pharmacology
disease activity
in patient

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