Effects of age, gender and urinary diversion category on perioperative complications of radical cystectomy

Objective To explore the association of age,gender and urinary diversion category with postoperative complications of radical cystectomy. Methods A total of 374 patients with bladder cancer undergoing modified radical cystectomy and urinary diversion between March 2000 and June 2011 were retrospectively reviewed. Their demographic, perioperative and complication data were recorded. And multivariable Logistic regression was used to investigate the predictors of perioperative complications.Results Among them,38.8％ (145/374) received ileal conduit,47.9％ (179/374) orthotopic ileal neobladder and 13.4％ (50/374) orthotopic colonic neobladder.The overall perioperative complication rate was 37.4％ (140/374).And 21.4％ (80/374)experienced at least one complication within Day 90 postoperation while 16.3 ％ (61/374)had the long-term complications ( ＞ Day 90).There was no significant association between patients age (P =0.15) and perioperative complications or between gender (P =0.16)and complication.Urinary diversion( OR =0.26,95％ CI:0.16 - 0.43 ) was the only variable significantly associated with the perioperative urinary complications.Conclusion The categories of urinary diversion may be used as a single predictor for complications after radical cystectomy. Key words: Bladder neoplasms; Cystectomy; Postoperative complications; Urinary diversion