Effect of Phyllanthus Amarus on the Acid and Alkaline Phosphatase Activity in Blood of Diabetic Induced Male Mice, Mus Musculus

Effect of Phyllanthus amarus, a medicinal plant as an alternative curing agent was administered to mice which were given alloxan treatment and also its enzyme titres were assessed. The enzymes connected with membrane permeability and absorption properties, such as acid phosphatase and alkaline phosphatase were studied. A significant increase was noticed in the acid and alkaline phosphatase activity was studied in blood after alloxan treatment and it was found that there was an increase in activity. The healing effect of Phyllanthus amarus was evident when it was injected after alloxan treatment and when it was given alone. The significance of these results is discussed. The substrates acid phosphatase and alkaline phosphatase blood studied in control, alloxan treated and alloxan with Phyllanthus amarus treated, and only Phyllanthus amarus treated animals. These components also showed similar fluctuations as that of acid and alkaline phosphatase. The significance of such fluctuation is discussed. The healing effect of Phyllanthus amarus and its inhibitory effect of alloxan induced diabetic is established beyond doubt by the results obtained in the present investigation.