Hаematologic indices in clinically healthy outdoor dogs exposed to vector-borne pathogens
2020
Introduction. Haematologic abnormalities possibly associated with exposure to
vector-borne pathogens are rarely reported in clinically healthy outdoor
dogs. Therefore, we analysed changes in the complete blood count (CBC) of
clinically healthy outdoor dogs seroreactive to Anaplasma spp. and Babesia
spp., with or without microfilariosis. Materials and Methods. Stray, shelter
and hunting dogs, 81 in total, that were polymerase chain reaction negative
for Anaplasma spp. and Babesia spp. were divided into groups according to
their seroreactive status and results of a modified Knott’s test:
seronegative to both Anaplasma spp. and Babesia spp. SN (N=26); seroreactive
to A. phagocythophilum SR-A (N=12); seroreactive to B. canis, B. gibsoni
and/or B. vogeli SR-B (N=25); and seroreactive to both of the pathogens SR-AB
(N=8). These four groups were negative to microfilariosis, unlike the fifth
group, seroreactive to either or to both of the pathogens and with
microfilariosis SR-M (N=10). Results and Conclusions. The frequencies of CBC
alterations among all analysed dogs were: 0.35 - leucocytosis, 0.44 -
granulocytosis, 0.28 - anaemia, 0.74 - microcytosis, 0.37 - increased mean
cell haemoglobin concentration (MCHC) and 0.33 - thrombocytopenia The
frequency of alterations did not differ across the groups. An exception was
the SR-M group wherein increased MCHC peaked with a frequency of 0.80, while
in the other four groups, the frequency ranged between 0.10 and 0.50.
Clinically healthy outdoor dogs have multiple CBC abnormalities, consistent
with stress and low-level chronic inflammation, but not associated with a
previous exposure to Anaplasma spp. or Babesia spp. The presence of
microfilaria increases haemolysis in vitro. [Project of the Serbian Ministry
of Education, Science and Technological Development, Grant no. 175061]
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