GVHD suppression by incubation of bone marrow grafts with anti-T-cell globulin: effect in the canine model and application to clinical bone marrow transplantation.

The present studies were performed in order to establish the anti-GVHD effect of an incubation treatment in the dog, which is regarded as a model of particular relevance for clinical bone marrow transplantation. Application of this principle to a case of human marrow transplantation will be reported.