Syntheses of pyrido [2,3-d] pyrimidine nucleosides via 6-allylaminouridines from 6,5'-anhydrouridine derivative and allylamines

Pyrido [2,3-d] pyrimidine nucleosides were readily synthesized by treatment of 2',3'-O-isopropylidene-6-allylaminouridines, which were derived from 6,5'-anhydro-2',3'-O-isopropylidene-6-hydroxyuridine and allylamines with palladium(II) acetate