Anti-PSGL-1

An antibody that specifically binds to P-selectin glycoprotein ligand-1 human without interfering with binding between P-selectin glycoprotein ligand-1 and P-selectin, wherein the antibody, upon binding to P-selectin glycoprotein ligand-1 on an activated T cell induces death of activated T cell, wherein the antibody comprises a first immunoglobulin chain is a light chain containing SEQ ID NOs: 1-3 and a second chain, a heavy chain, It is containing SEQ ID NOs: 4-6 for use in treating disease graft versus host disease (GVHD).