Solvent free synthesis of n-alkylated imino indoline-2-one derivatives under microwave irradiation

The solvent-free microwave-assisted syntheses of N-alkyl isatin Schiff base derivatives are reported. These isatin derivatives are obtained as a result of the condensation of an isatin compound with a benzyl halide and an aniline derivatives using microwave irradiation condition in high yield and short reaction time. KEY WORDS : Microwave, Isatin derivatives, Solvent free, Combinatorial synthesis Bull. Chem. Soc. Ethiop. 2018 , 32(2), 393-398. DOI: https://dx.doi.org/10.4314/bcse.v32i2.17