Vitamina D e asma brônquica Vitamin D and bronchial asthma

Vitamin D deficiency is now recognized as pandemic and with multifactorial causes. A growing number of studies on the adverse effects of vitamin D deficiency and its association with various pathologies, including bronchial asthma, has emerged. There are few studies that have evaluated the direct role of vitamin D in asthma, but there is increasing evidence that indirectly relates this vitamin with disease mechanisms. Many studies to date have attributed a role to vitamin D in asthma through many possible multifaceted interventions in the disease mechanisms. Thus, it is now acknowledged that vitamin D: Is involved in fetal lung growth and maturation; Higher prenatal intakes have a protective role against wheezing in small children; Normal serum levels reduce episodes of wheezing through its role in regulation of antimicrobial proteins or through its multiple immune effects; The presence of lower levels is associated with increased risk of asthma exacerbations; May have a therapeutic effect in patients with asthma resistant to corticosteroids.