In Vivo and Ex Vivo Confocal Microscopy for Nail Diseases

Nail diseases are often challenging to dermatologists. Reflectance confocal microscopy (RCM) is a noninvasive diagnostic tool that achieves a nearly histological resolution. It was initially developed for the evaluation of skin neoplasms, but more recently, it has also been applied for different diseases such as psoriasis, atopic dermatitis, lichen planus, mycosis fungoides, discoid lupus erythematosus, cutaneous infections, and infestations.