Amidines derivatives, their preparation and their use as medicaments.

The present invention relates to novel derivatives of amidines, their preparation and their application as medicaments. It relates in particular to the use of such derivatives for preparing a medicament intended to inhibit NO synthases (NOS) and / or monoamine oxidase (MAO). Recognizing the potential role of NOS and MAO in physiopathology, the new derivatives described corresponding to the formula ** ** that can produce beneficial or favorable effects in the treatment of diseases in which these enzymes are involved. Especially important are following conditions: - The problems of the central nervous or peripheral system such as neurological diseases that can be mentioned in particular Parkinson's disease, cerebral or spinal cord traumatisms, cerebral infarction, subarachnoid hemorrhage , epilepsy, aging, senile dementia, Alzheimer's disease, Huntington's chorea, amyotrophic lateral sclerosis, peripheral neuropathies, pain; - Schizophrenia, depressions, psychoses; - The problems of memory and mood; - pathologies such as migraine; - Behavioral problems, bulimia and anorexia; - autoimmune and viral diseases such as lupus, AIDS, parasitic and viral infections, diabetes and its complications (especially impotence linked to diabetes), multiple sclerosis; - addiction to toxic substances; - Inflammatory and proliferative diseases; - and more generally all pathologies characterized by excessive production of NOS and / or participation of MAO.