THE USE OF AMIDOPYRINE IN A CASE OF DIABETES INSIPIDUS

In July, 1932, Scherf 1 made a report on the use of amidopyrine in the treatment of diabetes insipidus. I had at that time a patient suffering from this disease whose only relief from the great frequency of urination was daily injection of a pituitary preparation. Numerous attempts to alleviate his symptoms by oral administration of large doses of desiccated pituitary gland, and by the intranasal use of sprays and tampons saturated with a potent preparation of double strength solution of pituitary or ampules of pitressin were all without avail. The use of a snuff made from desiccated whole pituitary gland was also ineffective, not the slightest relief being obtained from any of these procedures. The use of amidopyrine according to Scherf seemed to offer some hope. The patient, H. B., is a man, 6 feet (183 cm.) in height and weighing 160 pounds (72 Kg.). Before the onset of