Hyperuricemia as a risk factor for noninfectious diseases in the inhabitants of Chuvashia

: The relation of hyperuricemia with obesity, arterial hypertension, hyperlipoproteinemia, high intensity of lipid peroxidation, hyperinsulinemia, diabetoid carbohydrate disturbances (abnormal tolerance to carbohydrates and type-II diabetes mellitus) has been investigated in an epidemiological survey of a random population. The study covered 594 citizens of Chuvashia aged 16-65 years (mean age 39.4 +/- 0.5 years). Hyperuricemia is shown to be related with hyperlipidemia, arterial hypertension, obesity, high activity of lipid peroxidation and hyperinsulinemia. It is evident that on the population level hyperuricemia may serve an indicator of hormonal-metabolic athero-, diabetogenic shifts.