Inducible Depletion of Calpain-2 Mitigates Abdominal Aortic Aneurysm in Mice.

Latha Muniappan,Michihiro Okuyama,Aida Javidan,Devi Thiagarajan,Weihua Jiang,Jessica J. Moorleghen,Lihua Yang,Anju Balakrishnan,Deborah A. Howatt,Haruhito A Uchida,Takaomi C. Saido,Venkateswaran Subramanian

Inducible Depletion of Calpain-2 Mitigates Abdominal Aortic Aneurysm in Mice.

2021

Latha Muniappan
Michihiro Okuyama
Aida Javidan
Devi Thiagarajan
Weihua Jiang
Jessica J. Moorleghen
Lihua Yang
Anju Balakrishnan
Deborah A. Howatt
Haruhito A Uchida
Takaomi C. Saido
Venkateswaran Subramanian

Objective: Cytoskeletal structural proteins maintain cell structural integrity by bridging extracellular matrix with contractile filaments. During abdominal aortic aneurysm (AAA) development, (1) a...

Keywords:

Calpain-2
Abdominal aortic aneurysm
Calpain
Cell
Filamin
Cytoskeleton
Cell biology
Angiotensin II
Extracellular matrix
Chemistry

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