Comparative Effectiveness of Pegcetacoplan Versus Ravulizumab in Patients with Paroxysmal Nocturnal Hemoglobinuria Previously Treated with Eculizumab: A Matching-Adjusted Indirect Comparison

Rachel Y Bhak,Nikita Mody-Patel,Scott B. Baver,Colin Kunzweiler,Christopher Yee,Sanjana Sundaresan,Natalia Swartz,Mei Sheng Duh,Sangeeta Krishnan,Sujata P. Sarda

Comparative Effectiveness of Pegcetacoplan Versus Ravulizumab in Patients with Paroxysmal Nocturnal Hemoglobinuria Previously Treated with Eculizumab: A Matching-Adjusted Indirect Comparison

2020

Rachel Y Bhak
Nikita Mody-Patel
Scott B. Baver
Colin Kunzweiler
Christopher Yee
Sanjana Sundaresan
Natalia Swartz
Mei Sheng Duh
Sangeeta Krishnan
Sujata P. Sarda

In the absence of a head-to-head study, we assessed the comparative effectiveness of pegcetacoplan, a targeted C3 complement inhibitor, vs. ravulizumab, a C5 complement inhibitor, among patients wi...

Keywords:

in patient
indirect comparison
Internal medicine
Paroxysmal nocturnal hemoglobinuria
Gastroenterology
Eculizumab
Medicine
previously treated

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